DeRosa was diagnosed with a strained left wrist, and his DL stint is retroactive to July 1.
"He started to swing over the weekend and he was feeling improvement, but he still had some soreness as he started those workouts and that was just tee work," Cardinals manager Tony La Russa said.
DeRosa injured himself while swinging during an at-bat against the Giants on June 30. He has played in just three games for St. Louis after the Cardinals acquired him on June 27 from Cleveland for reliever Chris Perez and a player to be named.
"Down deep I thought we may hold him out for Milwaukee then still get him for the four [games] against the Cubs," La Russa said. "But I think the safest and smartest thing by far is just to make sure he gets the next 10 days, and hopefully when we can get him back [we can] keep him back."
The Cardinals also optioned infielder Tyler Greene to Triple-A Memphis on Monday. To replace DeRosa and Greene on the 25-man roster, the Cardinals recalled infielder Brian Barden and outfielder Nick Stavinoha from Triple-A Memphis. Barden hit .238 with four homers and 10 RBIs earlier this season with St. Louis, earning National League Rookie of the Month honors for April. Stavinoha batted .234 with a homer and 13 RBIs in 27 games with the Cardinals earlier this season.
Cash Kruth is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.