With Team USA trailing by four runs, Jimmy Rollins -- who had singled with one out -- was looking to make something happen and tried to swipe second with two outs.
It didn't work out, as Molina unleashed a laser throw. Second baseman Irving Falu was there to apply the tag for the third out, leaving Ryan Braun at the plate.
Molina is a big part of Puerto Rico's club. But on Saturday, manager Edwin Rodriguez is giving the All-Star a rest.
"We are still in Spring Training," the manager said. "As soon as the game starts, we'll try to win."
Figueroa was in complete control in his six innings, limiting Team USA to no runs on two hits.
Figueroa credited Molina for his game management.
"I had faith in the plan with Yadier Molina," the right-hander said. "To attack the strike zone."
In his last two World Baseball Classics, Figueroa has allowed two runs in 17 1/3 innings.
Team USA got on the board in the seventh inning. Joe Mauer tripled off Giovanni Soto and scored on Giancarlo Stanton's single.
Joe Frisaro is a reporter for MLB.com. He writes a blog, called The Fish Pond. Follow him on Twitter @JoeFrisaro. This story was not subject to the approval of Major League Baseball or its clubs.