"He came to me about two minutes before we exchanged lineup cards, so there was some mad-rushing going on to get everybody in place," Cardinals manager Mike Matheny said. "I think he did a smart thing and pulled up. He could have probably pushed through it. It was almost a low lat-back issue where it just tightened up while he was getting his swings in right before the game. I think he was smart by kind of putting on the brakes there.
"They went through treatment all game long. We'll take a look at him tomorrow. There's a good chance, good chance he won't be in there. That way he'd have the off-day too to make sure we're doing everything we can to stay away from this becoming something major. Right now it doesn't look like it's going to be that bad."
The Cardinals' left fielder had appeared in 58 of the team's 59 games this season.
Holliday, who was scheduled to hit clean-up for the first time this season before being scratched, is hitting .276 with nine doubles, one triple, 10 home runs, 35 RBIs, 38 runs scored, a .362 on-base percentage and a .458 slugging percentage.
The 32-year-old outfielder, who is in his fourth season with St. Louis, is a career .313 hitter and a five-time All-Star.