St. Louis manager Mike Matheny said that Friday's workout didn't go as well as Berkman hoped.
"He did do some running and it didn't go quite as well as he wanted," Matheny said. "So we're back to day to day. He'll probably rest a little more tomorrow, more therapy, and in a couple of days run him some more. But he's got one localized spot that seems to be grabbing.
"I do think he was expecting more. He'd been very vocal about feeling good. I think he was a little set back today. We'll reevaluate tomorrow and reevaluate on Sunday."
Matheny wouldn't completely count him out for the series in Houston.
"We'll see," he said.
Berkman, however, remained optimistic about his chances of playing against his former teammates. He has been out with a calf strain.
"I think there's a chance," Berkman said. "Couple of days, you never know."
Returning to Houston is always special, Berkman said.
"Every time I walk into this building you can't help but think of all kinds of good things that have happened here, on both sides now."