Milwaukee will counter with right-hander Wily Peralta in the second of a four-game series.
Peralta has averaged 96.2 mph on his fastballs this season, giving him the fourth-highest average fastball velocity -- counting four-seamers, two-seamers and sinkers -- among starters with at least 100 heaters thrown. Opponents have managed just a .198 weighted on-base average (wOBA) against those pitches, putting Peralta's fifth in that category (minimum 25 at-bats).
Through three starts this season, Peralta is 3-0 with a 2.65 ERA. Wainwright, though, is 0-3 through his first three outings of the season with a 7.24 ERA.
Three things to know about this game
• Wainwright has 14 wins in 28 career starts against the Brewers with a 2.16 ERA, the lowest mark in MLB history against Milwaukee among starters who have thrown at least 140 innings.
• The Brewers might have more information before Friday's game about the plan for veteran right-hander Matt Garza, who is ready to return from a season-opening stint on the disabled list for a right groin strain.
"Matt is going to be active here in the next week, but we have not decided what we are going to do," Brewers manager Craig Counsell said. "There's a couple of scenarios. It's day to day as far as what's going on with the bullpen, so we're going to kind of stay flexible in that regard."
• With Thursday's two hits, Eric Thames is on a 10-game run during which he is 16-for-33 with seven of his home runs, including a five-game streak on the road in which he homered six times. In those 10 games, Thames has scored 16 runs, drove in 11, hit four doubles and collected five walks while striking out just four times.
In his second life in the Major Leagues following three seasons in South Korea, Thames is the MLB leader in OPS (1.481), slugging percentage (.981), total bases (52), extra-base hits (14) and weighted runs created plus (287).
"I think the big thing for Eric is he's making a statement early in the season," Brewers manager Craig Counsell said. "It's big for our lineup. It's big for Ryan [Braun] having a guy ahead of him that they're going to have to be really careful with. He's just proving to be very dangerous."